Biotech Partners | Biotech Executive Search

Biotech Partners finds the talent that finds the cure.

Senior Scientist, Downstream Process Development

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  • Date Posted June 4, 2020
  • Location Seattle, Washington
  • Job Type Direct Hire
  • Job ID 2127

Ever dream of working for an industry leader in therapeutics for oncology/hematology, in a location with a rich culture and history, in a downstream process development position? We have the perfect position for you!

Our client is seeking a Senior Scientist (Downstream Process Development) in Seattle, WA!

Our client is an industry-leading organization in the biotech space that specializes in developing therapeutics to fight cancer. They utilize cutting-edge technology, their entrepreneurial culture and the most innovative minds in the field to develop science of what’s next in biotechnology.  This platform (modular protein technology) enables next-generation sequencing. Our client sets themselves apart with proprietary technology combined with a history of innovation, dedication and development.

Specific Responsibilities:

The Senior Scientist is a hands-on position and plays an integral role in planning, design of experiments, and the daily execution of the company’s Downstream Process Development function. The primary role will be to develop and transfer robust scalable purification processes to clinical manufacturers to produce bispecific protein therapeutics for clinical trials (70% laboratory and 30% office setting). The ideal candidate would have experience with operating bench scale purification instruments, utilizing multiple chromatography modes, characterizing purification processes and filing regulatory submissions such as IND/IMPD’s

  • Work with a team to achieve product milestones
  • Operation of purification equipment (program purification methods, execute purification, and collecting/presenting purification data)
  • Detailed planning of experiments in collaboration within the process development group and other groups
  • Participation in the planning of project timelines, deliverables and milestones
  • Authoring and receiving SOP’s, batch records, production protocols, deviation assessments, technical reports for GMP’s and CMC sections for regulatory filings
  • Preparation of buffers and other purification solutions appropriate to scale
  • Occasional travel, usually domestic

Qualifications:

  • Minimum education/experience in Chemical or biochemical engineering, or related field
  • Ph.D. and two plus years in industry
  • MS/MA ten plus years of relevant industry experience
  • BS/BA and twelve plus years of relevant industry experience

Qualified Candidates Please Send us your CV

Biotech Partners is one of the leading Life Sciences recruiting companies throughout the United States, placing qualified candidates with world-renowned organizations for over twelve years. Our recruiting consultants are experts in their markets and provide industry insights and interview coaching to their candidates throughout the engagement process.

Senior Scientist Upstream Process Development – BioReactors

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  • Date Posted January 24, 2020
  • Location Seattle, Washington
  • Job Type Direct Hire
  • Job ID 2022

Our client is seeking a Senior Scientist Upstream Process Development in Seattle, WA!

Our client is a biotech company primarily focused on bringing novel oncology and hematology therapeutics to the market. They are leveraging an innovative platform technology to cancer immunotherapy to ultimately improve outcomes for cancer patients. Offering breakthrough treatment options, our client attracts some of the most innovative minds in the field.

Specific Responsibilities:

The Senior Scientist is a hands-on position and plays an integral role in planning, design of experiments, and the daily execution of the Upstream Process Development function. The primary role will be to develop and transfer robust scalable mammalian cell culture processes to clinical manufacturers to produce bispecific protein therapeutics for clinical trials (70% laboratory and 30% office setting). The ideal candidate would have experience with operating bioreactors, CHO cell biology, protein expression and filing regulatory submissions such as IND/IMPDs.

  • Operation of bioreactors (inoculation, monitoring, and harvesting experimental or production bioreactor cell-cultures).
  • Detailed planning of experiments in collaboration within the Process Development group and other groups. Participation in the planning of project timelines, deliverables, and milestones.
  • Authoring and reviewing SOPs, batch records, production protocols, deviation assessments, technical reports for GMPs and CMC sections of regulatory filings.
  • Prepare cell-culture media and other cell-culture solutions appropriate to scale.
  • Frequent weekend work (usually ~2 hours at a time).
  • Occasional travel, usually domestic.

Qualifications:

  • Minimum Education/Experience in Chemical or Biochemical Engineering, Biochemistry, or related field:
    • Ph.D. and 2+ years relevant industry experience
    • MS/MA and 10+ years relevant industry experience
    • BS/BA and 12+ years relevant industry experience
  • Experience with developing cell-culture processes and the industrial scale-up of mammalian manufacturing cultures for clinical production of monoclonal antibodies or recombinant therapeutic proteins.
  • Ability to operate bioreactors of various types and sizes, filtration systems, cell counters and other instruments.
  • Ability to troubleshoot Upstream issues using knowledge, skills, precedents, and practices.
  • Experience in design of experiments (DoE), analysis of results, authorship of technical reports and presentations for both internal and external uses.
  • Knowledge of cGMPs and regulatory requirements for therapeutic biologics.
  • Excellent organization and communication skills.

Qualified Candidates, Please Send us your CV

Biotech Partners is one of the leading Life Sciences recruiting companies throughout the United States, placing qualified candidates with world-renowned organizations for over twelve years. Our recruiting consultants are experts in their markets and provide industry insights and interview coaching to their candidates throughout the engagement process